Dr. John Keith Nichols Medical Director and CEO

Benefits of using Pregnenolone

Pregnenolone exhibits a number of benefits to brain health:

  • Enhances memory
  • Improves focus and concentration
  • Improves cellular repair
  • Protects cerebral function
  • Prevents neuronal injury

Pregnenolone has also been studied for its benefits in treating anxiety, depression, and stress-related disorders, as well for treating marijuana addiction. Pregnenolone can also improve healing of nerve injuries.

Symptoms of Low Pregnenolone

The most obvious symptoms of low pregnenolone are poor memory and decreasing cognitive ability. This may be communicated as:

  • Having trouble remembering things
  • Just don’t feel as sharp as I used to
  • Difficulty with focus/concentrate/think straight

Dosage of Pregnenolone

We have all our patients take 100 mg of pregnenolone in a micronized, sustained-release capsule daily. It’s usually taken in the morning but can be taken in the evening.

We don’t measure pregnenolone levels because we’ve found they tend to be inconsistent and all our patients do well on the 100 mg dose. And the lab results are a guide post, since we focus more on how the patient feels.

How to Enroll in Our Telemedicine Program


Schedule a Consultation

Complete the form on this page and one of our team will call you back to help you get started on your optimization journey.


Physical & Lab Work

Get a physical exam from a healthcare provider near you and we will order the necessary bloodwork


Telemedicine Appointment

We’ll schedule your first telemedicine appointment.



We’ll enroll you in our program. Military, law enforcement, and firefighters get discounted rates. We also have convenient payment plans.


Custom HRT Plan

Based on your lab work and symptoms, we’ll create a custom BHRT plan that will be monitored and adjustments made monthly until your symptoms are resolved.


Follow up

You’ll have unlimited access to our HIPPA compliant patient portal and phone appointments at no additional charge. Any time you want to talk to us, we’re here for you.

Your Life Without Optimized Hormones

  • Weight gain, especially in midsection
  • Loss of lean muscle mass
  • Degenerative disease (diabetes, cancer, heart disease, osteoporosis)
  • Compromised immune system
  • Thinning of the skin.
  • Depression and stress
  • Cognitive decline/forgetfulness
  • Insulin resistance
  • Loss of sex drive
  • Fatigue
  • Sleep disorders
  • Muscle aches and pains
  • Bone loss
  • Heat/cold intolerance
  • Indecision
  • Erectile dysfunction
  • Thinning hair
  • Irritability
  • Hot flashes
  • Heart palpitations
  • Vaginal dryness


I’ve recommended hundreds of people to Tier1 Health & Wellness. If you’re a man or woman who’s looking to get your hormones optimized… I give them my highest endorsement

Jay Campbell

Best-selling author of the Testosterone
Optimization Therapy Bible


Schedule Your Free Consultation

Ready to get started? Just want to talk to a real person? Enter your details in the form and someone from our team will call you back within 24 hours.